Jove
Visualize
联系我们

相关概念视频

Atomic Force Microscopy01:08

Atomic Force Microscopy

3.3K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
3.3K
Studying the Cytoskeleton01:17

Studying the Cytoskeleton

5.8K
The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...
5.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sustainable AFM-Based Nanolithography on Chitosan Thin Films for 2.5D and 3D Nanostructure Fabrication.

Nanomaterials (Basel, Switzerland)·2026
Same author

Structure-property relationships of benzyl-substituted urea-based ligands with Phe-Phe linker targeting prostate-specific membrane antigen labeled with gallium-68.

Bioorganic chemistry·2026
Same author

Cathepsin Z/X: Breaking Down the Known and Unknown.

International journal of molecular sciences·2026
Same author

Chitosan Nanoparticles Unlock the Antioxidant Potential of Epigallocatechin Gallate in Pancreatic and Hepatic Cancer Cell Models.

ACS omega·2026
Same author

New redox-active Cu complexes with tridentate chelating ligands based on 2-thioimidazol-4-ones as potential antiproliferative agents.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Decoy Nanoparticles and Protein Corona Modulation: A Novel Frontier in Sepsis Treatment.

International journal of nanomedicine·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: May 22, 2025

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy
10:06

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy

Published on: July 10, 2019

7.3K

原子力显微镜:在癌症研究中的通用工具.

Francesca Persano1,2, Alessandro Parodi3, Tatiana Pallaeva3,4

  • 1Mathematics and Physics Department "Ennio De Giorgi", University of Salento, Via Arnesano, 73100 Lecce, Italy.

Cancers
|March 13, 2025
PubMed
概括

原子力显微镜 (AFM) 量化了以前未测量的细胞特性,推动了癌症研究. 这项技术为癌症攻击性和治疗疗效的临床诊断提供了潜力.

关键词:
原子力显微镜的原子力显微镜.癌细胞是一种癌细胞.细胞力学 细胞力学从上皮细胞到介质细胞的过渡.

更多相关视频

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells
09:27

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

3.8K
Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy Conpokal on Live Cells
09:20

Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy Conpokal on Live Cells

Published on: August 11, 2020

6.8K

相关实验视频

Last Updated: May 22, 2025

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy
10:06

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy

Published on: July 10, 2019

7.3K
Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells
09:27

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

3.8K
Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy Conpokal on Live Cells
09:20

Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy Conpokal on Live Cells

Published on: August 11, 2020

6.8K

科学领域:

  • 生物医学研究的研究.
  • 癌症生物学 癌症生物学
  • 纳米技术纳米技术

背景情况:

  • 新的分析方法正在彻底改变生物医学研究.
  • 原子力显微镜 (AFM) 越来越多地被纳入癌症研究中.
  • AFM使得以前忽视的细胞参数的量化成为可能.

研究的目的:

  • 审查AFM在生物医学和癌症研究中的关键作用.
  • 分析AFM在理解癌症细胞生物学和治疗反应方面的应用.
  • 考虑AFM的未来临床应用.

主要方法:

  • 机动飞行器使得分子和纳米级别的参数能够进行细致的监测.
  • 关键参数包括细胞形态,粗性,粘附性,刚性和弹性.
  • 这些参数与特定的细胞治疗相关,进行了研究.

主要成果:

  • AFM提供了对正常和治疗细胞的形态机械性质的洞察.
  • 该技术允许对细胞对治疗反应进行详细分析.
  • AFM的解决方案支持潜在的诊断应用.

结论:

  • AFM在促进癌症研究和了解治疗反应方面发挥着关键作用.
  • AFM具有临床采用潜力,有助于癌症诊断.
  • 该技术可以提供有关癌症攻击性和治疗疗效的宝贵信息.