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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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软组织肉瘤的系统治疗:我们有所作为吗?

Amrit Paudel1, Priya Chattopadhyay2, Brandon Rose2

  • 1Department of Medicine, Division of Medical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136, USA.

Cancers
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概括

软组织肉瘤 (STSs) 是一种罕见的,多样化的瘤. 目前的治疗包括手术和化疗,但高级的STS的生存率很低,需要新的治疗方法.

关键词:
这种类型的抗生素是Anthracyclines.化疗 化疗是一种化学疗法.免疫疗法 免疫疗法软组织肉瘤软组织肉瘤铁氨基激酶抑制剂 铁氨基激酶抑制剂

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科学领域:

  • 在瘤学瘤学.
  • 病理学 病理学 病理学
  • 遗传学 是一个遗传学.

背景情况:

  • 软组织肉瘤 (STS) 是一种罕见的癌症,起源于中皮组织.
  • 现存的亚型超过100种,每一种都有独特的临床行为和治疗反应.
  • 局部性STS治疗包括手术,放射和化疗,但转移是常见的.

研究的目的:

  • 审查软组织肉瘤 (不包括GISTs) 的当前全身治疗策略.
  • 为了突出STS治疗的最新进展.
  • 探索管理先进转移性STS的未来方向.

主要方法:

  • 对STS目前的全身疗法的文献综述.
  • 分析病理,免疫组织化学和分子特征,指导治疗.
  • 检查基于 antracycline 的化疗,向疗法和免疫疗法.

主要成果:

  • 基于人环素的化疗是高级STS的主要全身治疗方法.
  • 尽管目前的治疗方法,但最先进的STS亚型的存活率仍然很低.
  • 研究正在扩大除了化疗之外的治疗选择.

结论:

  • 整合分子数据的基因组学特定方法对于STS治疗至关重要.
  • 在先进的STS中提高反应率和生存率需要新的全身疗法.
  • 向治疗和免疫疗法代表了STS管理的未来有希望的方向.