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Updated: May 22, 2025

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

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寻找共同线索的研究:深入了解六种潜在抗癌剂的机制

Dóra Varga1,2, Anna Szentirmai1,2, András Szarka1,2

  • 1Laboratory of Biochemistry and Molecular Biology, Department of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Szent Gellért tér 4, H-1111 Budapest, Hungary.

Molecules (Basel, Switzerland)
|March 13, 2025
PubMed
概括

药理性 Askorbate (Ph-Asc) 和 Resveratrol (RES) 在癌细胞中诱导DNA双链断裂 (DSB). 氨酸 (CQ) 增强了这种效果,RSL3 诱导了胰腺癌细胞中独立于铁亡的DSB.

关键词:
在RSL3中使用RSL3.细胞死亡是细胞死亡.氨酸 (Chloroquine) 的使用情况药物重用是为了改变药物的用途.铁性化 (ferroptosis) 是一种梅纳迪奥尼 (Menadione) 是一种男性调节剂.药理学上的甲酸有活性氧物种的反应性氧物种.再组合癌症治疗疗法.复星醇是一种复星醇.

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