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Updated: May 22, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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比斯皮丁衍生物的金属复合物:取得的成就和未来的前景

Altynay B Kaldybayeva1,2, Valentina K Yu2, Feyyaz Durap3,4

  • 1Faculty of Chemistry and Chemical Technology, Al Farabi Kazakh National University, 71 Al-Farabi Ave, Almaty 050040, Kazakhstan.

Molecules (Basel, Switzerland)
|March 13, 2025
PubMed
概括

比斯皮丁连接物形成稳定的金属复合物,具有可调节的特性. 由于它们独特的协调行为,这些复合物在放射性药物,药物化学和催化剂方面表现有前途.

关键词:
比斯皮丁 (bispidine) 是一种可怕的药物.双素框架 双素框架催化剂是一种催化剂.金属复合体金属复合体放射性药物制品 放射性药物制品综合合成是一种合成.

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Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
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