水氧酸盐与光生物调节结合用于骨组织修复:系统性审查
Camila Pascoal Correia Dos Santos1, Paola Tatiana Espinosa Cruel1, Daniela Vieira Buchaim2,3
1Graduate Program in Applied Dental Sciences, Bauru School of Dentistry, University of Sao Paulo, Bauru 17012-901, Brazil.
Materials (Basel, Switzerland)
|March 13, 2025
概括
与光生物调制 (PBM) 结合的酸 (CaHA) 显示出对骨再生的前景. 本次审查强调了对软组织应用和CaHA和PBM疗法的标准化方案进行更多研究的需要.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 生物光子学 生物光子学
背景情况:
- 硬组织修复,特别是骨再生,带来了重大的临床挑战.
- 酸 (CaHA) 具有良好的生物相容性和生物活性,模仿天然的骨矿物质.
- 光生物调制 (PBM) 是一种利用光来促进愈合和减少炎症的治疗方式.
研究的目的:
- 系统地审查有关CaHA和PBM用于组织再生的联合使用的现有文献.
- 在结合CaHA和PBM的研究中确定常见的材料,波长和应用.
- 评估CaHA和PBM在再生医学中的当前状态和未来方向.
主要方法:
- 在PubMed,Web of Science和ScienceDirect数据库中进行了系统的文献搜索.
- 关键词包括"酸和光生物调节"",酸和光生物调节"和"低水平激光疗法和酸".
- 分析包括了25项专注于骨再生的研究.
主要成果:
- 大多数研究 (76%) 使用双相酸盐,即CaHA和β-三酸盐的组合.
- 808nm和780nm的红外激光波长是PBM中最常用的 (分别为24%).
- 所有包括的研究都专注于骨再生,没有报告软组织应用.
结论:
- CaHA和PBM的组合显示出在牙科和再生医学中骨再生应用的潜力.
- 进一步的研究对于探索软组织应用和为临床使用开发标准化协议至关重要.
- 需要扩大实验和临床研究,才能充分认识到CaHA和PBM的治疗益处.
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