纤维摄入量与肠道细菌多样性和组成在怀孕第三个月的关系
Lindsay T Schwartz1, Jillian G Ladouceur1, Madeleine M Russell1
1Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824, USA.
Nutrients
|March 13, 2025
概括
大多数孕妇不符合纤维摄入量建议,影响了他们的肠道微生物群多样性. 提高怀孕期间的纤维摄入量对于母亲的健康和肠道细菌组成至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 微生物组研究 微生物组研究
- 营养科学 营养科学
背景情况:
- 在怀孕期间推高纤维饮食,以减少便秘,子宫前和妊娠糖尿病的风险.
- 怀孕期间纤维的保护机制尚未完全理解,可能涉及肠道微生物群.
- 食纤维通过其对肠道细菌组成和功能的影响,可能会影响怀孕健康结果.
研究的目的:
- 评估孕妇参与者是否符合每日纤维和蔬菜摄入量建议.
- 研究纤维和蔬菜摄入量对肠道微生物组的细菌组成的影响.
- 检查孕期肠道微生物群中食纤维摄入量与丁酸盐产生基因之间的关系.
主要方法:
- 分析了便样本和调查数据从52名孕妇参与者在他们的第三个三个月.
- 基于调查数据计算食纤维和蔬菜摄入量.
- 16S rRNA基因测序和定量实时PCR分析细菌组成和基因丰富度.
主要成果:
- 大多数参与者 (84.7%的纤维,92.3%的蔬菜) 没有达到推摄入量的水平.
- 符合纤维建议的参与者表现出更大的肠道微生物群α多样性 (香农和逆辛普森指数).
- 在食纤维摄入量和负责酸盐生产的细菌基因的丰富性之间没有发现任何关联.
结论:
- 怀孕期间的一般纤维摄入量与肠道细菌社区结构的适度关联.
- 初步发现强调了需要改善孕妇饮食纤维的需求.
- 需要进一步的研究来探索特定纤维类型对肠道细菌及其在怀孕期间的功能的影响.
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