相关实验视频
Updated: May 22, 2025

09:18
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
Published on: July 28, 2023
2.4K
肠道胜过思想:探索强大的肠道-大脑轴.
Stefana-Maria Petrut1, Alexandra Maria Bragaru2, Alice Elena Munteanu3,4
1Department of Preclinical Sciences, Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania.
Nutrients
|March 13, 2025
概括
益生菌调节肠道微生物群,影响消化,免疫力和心理健康. 肠-大脑轴揭示了肠道健康和精神健康之间的深层联系,影响了情绪和行为.
科学领域:
- 微生物学 微生物学
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
背景情况:
- 人的肠道拥有各种微生物,包括食物中发现的有益益生菌.
- 众所周知,益生菌调节肠道微生物群,对消化,新陈代谢,免疫功能和心理健康至关重要.
研究的目的:
- 审查了解胃肠道系统与大脑之间的关系的最新进展.
- 探索肠道微生物群对心理健康的影响.
主要方法:
- 一个叙述性回顾过去十年的原创研究.
- 在PubMed.com进行的文献搜索.
主要成果:
- 新兴研究强调了肠道微生物群在影响心理健康方面的关键作用.
- 微生物群-肠-大脑轴是一个双向通信网络,连接中枢神经系统和胃肠道.
- 这个轴表明了肠道健康和大脑功能之间的深刻联系,影响了情绪和行为.
结论:
- 了解微生物群的组成和肠-大脑相互作用机制是未来医学和治疗策略的关键.
- 对大脑-肠轴的洞察力可以彻底改变心理健康和胃肠道疾病的治疗方法.
相关概念视频
Neural Regulation
39.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.0K
Hormonal Regulation
43.1K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
43.1K
Physiology of Enteric Nervous System and Gut Health
209
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
209
Irritable Bowel Syndrome I: Introduction
213
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
213
Neurotransmitters
761
Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
761
Enteric Nervous System: Regulation of GI Motor Activity
279
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
279

