孕产妇的肥胖和子女的神经发育
Anna Eleftheriades1, Sevasti Koulouraki1, Antonios Belegrinos2
1Second Department of Obstetrics and Gynaecology, Aretaieion Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Nutrients
|March 13, 2025
概括
怀孕期间母亲的肥胖与儿童的神经发育障碍有关. 需要进一步的研究来证实这种关联,并探索遗传和环境因素.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 公共卫生 公共卫生
背景情况:
- 越来越多的证据表明,怀孕期间母亲的肥胖与后代的不良神经发育结果有关.
- 诸如ADHD,自闭症谱系障碍,智力障碍和脑等疾病与子宫内暴露于母亲肥胖症有关.
研究的目的:
- 研究母亲肥胖和后代神经发育结果之间的关联.
- 总结当前关于将孕产妇肥胖与神经发育问题联系起来的潜在机制的证据.
主要方法:
- 在Medline/PubMed和Google Scholar进行了全面的文献搜索.
- 关键词包括孕产妇肥胖,孕产妇超重,孕产妇饮食,神经发育和神经精神疾病.
- 两个独立审查员进行了搜索和数据提取.
主要成果:
- 该评论总结了有关炎症,激素失调,微生物组变化和表观遗传学等机制的证据.
- 包括动物研究支持母亲肥胖和后代神经发育之间的联系.
结论:
- 母亲肥胖似乎与后代的各种神经精神和神经发育障碍有关.
- 需要更强大的研究来证实这种关联,考虑到诸如遗传学和基因环境相互作用等混因素.
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