评价Centranthera grandiflora的成分,营养素,抗氧化和抗炎性质和Benth提取物
Wenjuan Yuan1,2, Xinlan Liu2,3, Xinting Wang2,3
1College of Science, Yunnan Agricultural University, Kunming 650201, China.
Nutrients
|March 13, 2025
概括
百合花 (Centranthera grandiflora Benth) 提取物 (CGE) 显示出良好的营养特征以及强大的抗氧化和抗炎作用. 它通过调节Nrf2/HO-1和PI3K/Akt/NF-κB通路而起作用,这表明它可以作为食补充剂.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 营养科学 营养科学
背景情况:
- 花 (Centranthera grandiflora Benth) 在中国传统上用于健康益处.
- 对其化学成分,营养价值和生物活性进行表征是必不可少的.
研究的目的:
- 研究Centranthera grandiflora Benth提取物 (CGE) 的营养价值,生物安全性和生物活性.
- 阐明CGE抗氧化和抗炎作用的潜在机制.
主要方法:
- 使用UPLC-ESI-Q-TOF/MS.进行化学成分分析.
- 网络药理学和分子对接用于机制探索.
- 在RAW264.7细胞上进行体外测试,以评估抗氧化和抗炎活性.
主要成果:
- CGE具有良好的营养和生物安全性,富含氨基酸和矿物质.
- 鉴定了20种化合物,突出显示了musaenoside和azafrin作为关键的生物活性化合物.
- 通过调节Nrf2/HO-1和PI3K/Akt/NF-κB通路,降低氧化应激和炎症标志物,CGE显示出显著的抗氧化和抗炎作用.
结论:
- CGE是一种丰富的虹膜糖化物和其他营养素来源.
- 由于其健康益处,CGE具有作为食品应用中宝贵的食补充剂的潜力.
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