血小板丰富血与侧面表皮炎的皮质类固醇:随机临床试验的元分析
Ralph Maroun1, Mohammad Daher1, Peter Boufadel1
1Division of Shoulder and Elbow Surgery, Rothman Orthopaedic Institute, Thomas Jefferson Medical Center, Philadelphia, PA, USA.
Clinics in shoulder and elbow
|March 13, 2025
概括
皮质类固醇注射为网球手肘提供优越的短期疼痛缓解,而富血小板血注射提供更好的长期疼痛和功能改善. 这两种治疗都是有效的,但PRP显示出更好的长期结果.
科学领域:
- 整形外科 整形外科 整形外科
- 再生医学是一种再生医学.
- 运动医学 运动医学
背景情况:
- 侧面表皮质炎 (网球肘) 是一种普遍的疾病,导致肘部疼痛和功能障碍.
- 它通常与重复的动作有关,并影响中年人.
- 由于病情的经济影响,正在研究非手术注射治疗的有效性.
研究的目的:
- 为了比较富血小板血 (PRP) 和皮质类固醇 (CS) 注射用于管理侧面表皮质炎的临床有效性.
- 根据疼痛减轻和功能改善来评估结果.
- 综合随机对照试验 (RCT) 的证据.
主要方法:
- 对PubMed,Cochrane和谷歌学者进行了系统的搜索,截至2024年3月.
- 在元分析中仅包括随机对照试验 (RCT).
- 使用视觉模拟尺度 (VAS) 评估疼痛和手臂,肩膀和手的残疾 (DASH) 评分用于功能.
主要成果:
- 分析了26个涉及1877名患者的RCT.
- 与PRP相比,皮质类固醇注射显示出更好的短期疼痛缓解 (VAS) (<2个月).
- 富血小板血注射显示出优异的长期疼痛缓解 (VAS) 和功能改善 (DASH) (>6个月).
结论:
- 皮质类固醇注射可为侧面表皮炎提供快速的短期疼痛缓解.
- 富血小板血注射提供优越的长期疼痛管理和功能恢复.
- 未来的研究应该探索替代注射方案和辅助的非侵入性疗法.
更多相关视频
14:38Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
18.0K
05:18Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
1.3K
相关概念视频
01:24Local Anesthetics: Differential Sensitivity of Nerve Fibers
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
01:25Acute Inflammation III: Local and Systemic Effects
Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...