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Updated: May 22, 2025

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
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一个微型的低免疫性平台,用于自组装蛋白质纳米粒子的生物合成

Almina I Polinova1, Anna V Serkina1, Marina V Volkova1

  • 1National Research Center «Kurchatov Institute», Moscow, 123182, Russia.

Nanotheranostics
|March 13, 2025
PubMed
概括

研究人员开发了一个新的自组装蛋白纳米粒子 (SAPN) 平台,使用 pepA1.1. 这种改进的疫苗平台在没有辅助剂的小鼠中显示出100%的血清转化率,显示出未来疫苗开发的前景.

关键词:
在N端的甲基甲氨酸.在OVA257-280抗原.人工疫苗平台的人工疫苗平台免疫性 免疫性 免疫性自组装蛋白质纳米粒子自组装蛋白质纳米粒子自结合的自我结合.一个子单位的疫苗.

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Protein Complex Assembly02:41

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