肥胖患者上肢手术的无阿片类麻醉作为一天的外科手术:一项前性观察性研究
Rana Ahmed Abdelghaffar1, Mohamed Ahmed Hamed1, Mohammed Magdy Basiony1
1Department of Anesthesiology, Faculty of Medicine, Fayoum University, Faiyum Governorate, Egypt.
Anesthesiology and pain medicine
|March 13, 2025
概括
与基于阿片类药物的麻醉 (OBA) 相比,在接受上肢手术的肥胖患者中,无阿片类麻醉 (OFA) 显示疼痛减少,住院时间缩短,并发症减少. 建议进行进一步的研究来证实这些益处.
科学领域:
- 麻醉学 麻醉学
- 肥胖医学 肥胖医学
- 外科手术的结果
背景情况:
- 无阿片类麻醉 (OFA) 是一种新兴的方法,需要进一步研究.
- 需要进行比较性研究来评估OFA与传统的阿片类麻醉 (OBA) 相比.
研究的目的:
- 研究OFA在接受上肢手术的肥胖患者的疗效和安全性.
- 在这个患者群体中,比较OFA与OBA的结果.
主要方法:
- 一项前性随机临床研究,涉及76名肥胖患者 (BMI ≥30 kg/m2).
- 患者被随机分配到OFA (利多卡因,普罗波,阿特拉库里安,德克斯米德托米丁) 或OBA (普罗波,芬太尼,阿特拉库里安).
- 结果包括术后疼痛 (VAS),救援特拉马多尔,输出时间,血液动力学稳定性,PONV和住院.
主要成果:
- 在OFA组显示出显著较低的输出时间,平均动脉压和心率.
- 在OFA组中,在30分钟和2小时后的输出术后观察到下视觉模拟量 (VAS) 疼痛评分.
- 较少的不良事件,减少了救援需要和更短的住院时间被记录在OFA.
结论:
- 无阿片类药物麻醉可以为接受上肢手术的肥胖患者提供更好的和更安全的结果.
- OFA与手术后并发症减少和住院时间缩短有关.
- 需要进行额外的研究才能充分阐明OFA与OBA之间的优势.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
38
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
38
Local Anesthetics: Clinical Application as Spinal Anesthesia
568
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
568
General Anesthesia: Overview
183
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
183
Local Anesthetics: Clinical Application as Epidural Anesthesia
404
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
404
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
339
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
339


