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Updated: May 22, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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阻塞性睡眠呼吸暂停和缺血性中风之间的遗传重叠:一个大规模的全基因组横向分析

Wanqing Lin1,2, Zhiyi Zhang3, Chenlin Wang4

  • 1Department of Rehabilitation Medicine and National Clinical Research Base of Traditional Chinese Medicine, The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian Province, 350004, People's Republic of China.

Nature and science of sleep
|March 13, 2025
PubMed
概括

遗传因素在阻断性睡眠呼吸暂停 (OSA) 和缺血性中风的并发症中发挥着重要作用. 这项研究确定了共享的遗传架构和类单核酸多态 (SNP) 联系这些条件.

关键词:
在GWAS中,GWAS就是GWAS.遗传上的重叠是遗传上的重叠.缺血性中风 中风阻塞性睡眠呼吸暂停症是什么

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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