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中枢神经系统的原发性血管炎及其模仿:一种基于模式的方法,用于中枢神经系统血管炎的活检

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  • 1From the Department of Pathology, University of Michigan, Ann Arbor.

Archives of pathology & laboratory medicine
|March 13, 2025
PubMed
概括

主要中枢神经系统血管炎的诊断需要确定血管炎症. 当血管炎不存在时,在脑活检中识别替代性炎症模式对于准确诊断至关重要.

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...