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Updated: May 22, 2025

Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides
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一个与ER相关的结构封存了错误组装的富含FG的核波林,以帮助维持核孔复合物的功能

Madison Pletan1,2, Emily Wang1, Luke Gohmann1,2

  • 1Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48104, USA.

Journal of cell science
|March 13, 2025
PubMed
概括

细胞内膜网膜 (ER) 在ER焦点中将错误组装的核素 (Nups) 隔离,防止核孔综合体 (NPC) 功能障碍. 这种ER封存机制对于维持核-细胞质运输至关重要,并可能影响神经退行性疾病.

关键词:
细胞内膜网膜是什么 细胞内膜网膜核膜运输是核膜的运输方式.蛋白质质量控制 蛋白质质量控制

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