为了减轻长期微粒物质暴露的心血管影响,假设的行为干预:来自2个潜在队列的分析
Jialong Wu1, Liang Wang2, Xu Han3
1West China School of Public Health and West China Fourth Hospital Sichuan University Chengdu Sichuan China.
采用更健康的行为可以显著降低与细颗粒物 (PM2.5) 暴露相关的心血管疾病 (CVD) 风险. 这些生活方式的改变补充了减轻PM2.5的排放控制.
科学领域:
- 环境健康科学 环境健康科学
- 心血管疾病流行病学
- 公共卫生干预措施 公共卫生干预措施
背景情况:
- 环境细颗粒物 (PM2.5) 与心血管疾病 (CVD) 之间的关联是一个重大的公共卫生问题.
- 目前尚不清楚健康行为是否可以减轻PM2.5暴露的不良心血管影响.
研究的目的:
- 通过假设的行为干预来量化PM2.5对心血管疾病影响的潜在减少.
- 评估个人和联合健康行为对PM2.5相关心血管疾病风险的影响.
主要方法:
- 利用参数g-公式在各种干预场景下建模潜在风险降低.
- 分析了来自英国生物银行 (UKB) 和四川队列 (中国多民族队列,四川地区) 的数据.
- 根据现实的和理想的行为变化定义了"可行的"和"密集的"干预场景.
主要成果:
- 长期暴露于PM2.5与两个队伍中心血管疾病发病率的增加有关.
- 改善饮食,身体活动和体重指数显著降低了PM2.5的心血管疾病风险影响,降低范围从4.59%到37.22%.
- 对六种行为进行联合干预,可以将PM2.5的心血管疾病效应降低19.75%-31.47% (可行) 至45.54%-57.51% (密集).
结论:
- 更健康的行为可以作为个人层面的策略来减少PM2.5.5的健康负担.
- 这些行为干预措施补充了空气污染排放控制措施.
- 这些发现适用于高污染和低污染地区,以尽量减少PM2.5对健康的影响.
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