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Updated: May 22, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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脂酶-联合催化动态动态动力学分辨率的 Racemic 基 Ester 的

Masato Oono1, Akane Yamada2, Masanari Kimura3

  • 1Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Chemistry (Weinheim an der Bergstrasse, Germany)
|March 13, 2025
PubMed
概括

这项研究引入了使用新型催化剂和乙酸的种族性基的改进动态动态分辨率 (DKR). 这种方法可以有效地产生具有高产量和酶选择活性的光学活性合醇.

关键词:
艾利醇是一种醇.动态运动分辨率的动态动态分辨率.水解是指水解过程中的水解.脂酶脂酶的使用方法帕拉是一种.

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