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Updated: May 22, 2025

CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells
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克劳丁-11通过MT1-MMP激活增强小细胞肺癌的侵入性和转移性能力

Shuichi Sakamoto1, Hiroyuki Inoue1, Takahisa Takino2

  • 1Institute of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Research Foundation, Numazu, Japan.

Cancer science
|March 13, 2025
PubMed
概括

克劳丁-11促进小细胞肺癌 (SCLC) 转移,通过激活MT1-MMP,这是细胞外矩阵降解中的关键酶. 这种克劳丁-11/MT1-MMP通路对于SCLC进展和患者预后不佳至关重要.

关键词:
在MT1-MMP之间.在SCLC中,SCLC是最重要的.克劳丁‐11是一种这是入侵的入侵.转移 转移 转移 转移

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