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Updated: May 22, 2025

siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells
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两体在HBV的产生和通过内体和自道释放中发挥作用

Jia Li1, Thekla Kemper1, Ruth Broering2

  • 1Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Hepatology communications
|March 13, 2025
PubMed
概括

乙型肝炎病毒 (HBV) 的产生和释放涉及自细胞-晚期内细胞路径. 抑制胺转运或RAB27A/B会损害HBV的分泌,这表明与外体细胞有共同的途径.

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Delivery Pathways to the Lysosome

Eukaryotic cells use different mechanisms to eliminate toxic waste obsolete and worn-out substances. Lysosomes play a pivotal role in this, and hence, these substances are carried to the lysosome from other parts of the cell and extracellular space through different pathways. The most elaborately studied pathways to the lysosome are the endocytic pathways.
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Intralumenal Vesicles and Multivesicular Bodies

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The recycling endosome, also known as the endosomal recycling compartment (ERC), is a part of the slow-recycling process of the endocytic pathway. Molecules internalized through receptor-mediated endocytosis are either degraded in the lysosomes or are recycled to the plasma membrane through the fast- or slow-recycling route.
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