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Updated: May 22, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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对纳皮拉ዲዮ米辛家族的见解:结构,生物活性和生物合成途径

Nuo Chen1,2, Zinian Zhang1,2, Hangzhen Lan2

  • 1Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, Health Science Center, Ningbo University, Ningbo, Zhejiang, 315211, China.

Archives of microbiology
|March 13, 2025
PubMed
概括

纳皮放射菌素 (NPD) 是具有多样性结构和生物活性的强效天然产品. 这篇评论探讨了它们的化学,生物合成和对抗耐药细菌和癌症的治疗潜力.

关键词:
这种病名为Streptomyces.抗菌剂 抗菌剂 抗菌剂生物合成生物合成细胞毒性 细胞毒性原酶是一种基酶.纳皮拉迪奥米辛 (Napyradiomycins) 是一种天然的酸盐.

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Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
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