相关实验视频
Updated: May 22, 2025
05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
1.2K
疑似颗粒瘤与多炎呈现前硬化炎和炎症性纤毛体颗粒瘤
Negin Yavari1, Hashem Ghoraba1, S Saeed Mohammadi1
1Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Journal of ophthalmic inflammation and infection
|March 13, 2025
概括
本案例研究突出了成功治疗涉及硬化症的多炎 (GPA) 有限颗粒瘤的成功治疗方法. 系统性rituximab (RTX),mycophenolate mofetil和静脉内德克萨梅他松植入物有效地管理了耐治疗的眼睛炎症.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 有限的多炎颗粒状瘤 (GPA) 可以呈现眼部表现,包括硬化症.
- 体炎性粒瘤是一种罕见但严重的并发症,与GPA相关.
- 眼睛GPA的管理可能具有挑战性,需要多模式的治疗方法.
研究的目的:
- 报告一个疑似有限的GPA病例与前硬化和体颗粒瘤.
- 为了评估组合治疗的疗效,包括rituximab (RTX),mycophenolate mofetil和静脉内 (IVT) dexamethasone植入物.
- 强调早期诊断和针对眼部GPA的量身定制治疗的重要性.
主要方法:
- 一名患者被认为具有有限的GPA,部门硬化和体颗粒瘤被治疗.
- 最初的治疗包括静脉注射甲基prednisolone和口服甲铁酸盐.
- 随后的治疗包括全身RTX,口服mycophenolate mofetil和IVT甲植入物.
主要成果:
- 包括鼻活检和视切除术在内的诊断调查对恶性瘤,真菌和细菌感染呈阴性.
- 只有在开始RTX,mycophenolate mofetil和IVT德克萨米他松植入物后,患者才出现显著改善.
- 这种组合疗法对抗治疗的眼球炎症有好处.
结论:
- 与有限的GPA相关的硬化症 presents一个治疗挑战.
- 早期诊断和及时干预对于预防并发症至关重要.
- 利图西马布,美酸莫菲蒂尔和静脉内甲胺植入物为难治性眼球GPA病例提供了可行的治疗选择.
相关概念视频
01:25Glaucoma: Overview
488
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
488
01:28Angle Closure Glaucoma: Treatment
420
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
420
01:27Open Angle Glaucoma: Treatment
378
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
378