利用研究能力提升,在巴基斯坦开发和实施国家标准护理治疗方案
Mohiba A Khowaja1, Alia Ahmad2, Sadaf Altaf3
1Pakistan Society of Pediatric Oncology (PSPO), Karachi, Pakistan.
JCO global oncology
|March 13, 2025
概括
巴基斯坦儿科瘤学会 (PSPO) 成功实施了儿童癌症的国家标准护理 (SOC) 协议,改善了巴基斯坦的研究基础设施. 这一举措证明了低资源环境的可行性.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 公共卫生 公共卫生
背景情况:
- 临床研究方法对于改善儿科癌症结果至关重要.
- 世界卫生组织的儿童癌症全球倡议 (GICC) 旨在改善全球儿童癌症护理.
- 由于资源有限,巴基斯坦在儿童癌症治疗方面面临挑战.
研究的目的:
- 描述在巴基斯坦为儿童癌症制定和实施国家标准护理 (SOC) 协议的战略.
- 建立一个集中式的研究和数据管理支持系统.
- 为未来在巴基斯坦儿科癌症护理方面的进步奠定基础.
主要方法:
- 巴基斯坦儿科瘤学会 (PSPO) 中央办公室为协议开发和数据管理提供了支持.
- 多机构团队根据国际证据和当地数据为六个针对GICC的诊断制定了SOC协议.
- 在案例报告表格和数据库中使用了RedCap软件,通过审计和分析进行了全面的培训和持续的数据质量维护.
主要成果:
- 协议的制定和实施在26个月内完成.
- 每个协议都至少在七个中心活跃,注册了近2000名患者.
- 对急性淋巴细胞白血病 (ALL) 数据的临时分析表明数据准确率为85%.
结论:
- 在资源有限的低收入和中等收入国家,实施多机构治疗方案是可行的.
- 通过合作努力,可以建立研究基础设施和能力.
- PSPO的方法提供了一个可扩展的模型,用于改善资源有限的环境中的儿科癌症护理.
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