确保代表性:对增加少数群体参与癌症相关研究的干预措施进行全面审查
David Lewis Pottinger1, Soumya Niranjan2, Nusrat Jahan3
1Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, AL.
JCO oncology practice
|March 13, 2025
概括
定制教育和患者导航等策略显著促进少数群体参与癌症临床试验 (CCT). 所有经过测试的干预类别都显示出改善CCT多样性和减少健康不平等的前景.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康 公平 卫生 公平
背景情况:
- 在癌症临床试验 (CCT) 中少数群体的代表性不足损害了研究的概括性,并加剧了健康差异.
- 少数群体在公共公共技术中的参与不足对癌症治疗的公平进步构成重大威胁.
研究的目的:
- 进行范围审查,检查旨在加强少数民族参与和保留在CCT中的干预措施.
- 识别和分类促进在癌症研究中纳入不同人群的策略.
- 评估不同干预类别在改善少数民族入学率方面报告的有效性.
主要方法:
- 在EMBASE,Scopus和PubMed数据库中进行了全面的文献搜索.
- 包括专注于增加少数民族入学/留学率的干预措施的研究,并报告了干预强度的客观指标.
- 需要进行研究来比较干预与对照或其他干预措施.
主要成果:
- 在817篇确定文章中,37篇符合纳入标准,揭示了五个干预类别:教育干预 (17),患者导航 (12),社区参与 (8),自主招聘 (4) 和财政激励 (4).
- 教育干预 (7/10) 和患者导航 (5/5) 显示少数群体参与的显著改善.
- 社区参与 (1/1),自主招聘 (2/2) 和财政援助 (1/3) 也显示出前景,表明不同战略的有效性各不相同.
结论:
- 量身定制的教育干预和患者导航对于增加少数群体参与CCT至关重要.
- 虽然所有审查的干预类别都显示出潜力,但需要进一步的研究来评估多方面的方法.
- 确保少数群体充分参与CCT对于促进癌症护理平等至关重要.
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