了解越南的早期喷泉衰竭:发生率和临床预测因素
Dac-Dai Tran1,2,3, Ngoc-Thanh Le1,2, Hai-Van T Dang4,5,6
1Cardiovascular Center, E Hospital, Hanoi, Vietnam.
World journal for pediatric & congenital heart surgery
|March 13, 2025
概括
在9.66%的患者中发生了早期的Fontan衰竭 (EFF),肺动脉压力升高和心室门修复是关键预测因素. 综合管理策略对于防止EFF,特别是在资源有限的环境中至关重要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 生产性心脏病 手术 手术 生产性心脏病
- 研究成果 研究成果 研究成果
背景情况:
- 芬坦手术是一种治疗单心室先天性心脏缺陷的缓解手术.
- 早期Fontan故障 (EFF) 仍然是一个重大问题,影响长期结果.
- 在越南等发展中国家,EFF发病率和风险因素的数据有限.
研究的目的:
- 在越南患者队列中确定早期Fontan衰竭 (EFF) 的发生率.
- 确定与EFF相关的手术前,手术内和手术后的风险因素.
- 在资源有限的医疗保健机构中,为预防EFF制定战略提供信息.
主要方法:
- 从2012年8月到2019年12月,连续145名患者接受了Fontan手术的回顾性分析.
- 用临床评估,文献审查和机构数据库分析来确定风险因素.
- 使用多变量逻辑回归来确定EFF的独立预测因子.
主要成果:
- 欧洲粮食基金的发病率为9.66%.
- 统一分析确定了与EFF相关的不平衡的心房隔膜缺陷,逆位,AV反,肺动脉压力升高 (PAP) 和肺血管抵抗 (PVR).
- 多变量分析揭示了手术前升高的PAP,手术内心室 (AV) 门修复,以及手术后升高的PAP作为EFF的独立预测因素.
结论:
- 在这个越南系列中,早期的Fontan故障相对较高,并且与显著的死亡率有关.
- 手术前升高的PAP,手术内AV门修复和术后升高的PAP是EFF的独立预测因素.
- 针对这些预测因素的综合管理策略对于防止EFF,特别是在发展中国家,至关重要.
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