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Updated: May 22, 2025

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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高瘤突变负担减轻了化疗史对免疫检查点阻塞疗法的负面影响

Ming Zheng1

  • 1Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Academy of Military Medical Sciences, 27 Taiping Road, Beijing 100850, China.

Seminars in oncology
|March 13, 2025
PubMed
概括

之前的化疗降低了免疫检查点抑制剂 (ICI) 在肺癌中的有效性,特别是在低瘤突变负担 (TMB) 的患者中. 高TMB可能会克服这种抗性,建议ICI作为一些患者的第一线选择.

关键词:
化疗 化疗是一种化学疗法.免疫检查点抑制剂 免疫检查点抑制剂免疫治疗是一种免疫疗法.非小细胞肺癌的非小细胞肺癌.

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