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Updated: May 22, 2025

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性别特定的UGT表达和功能:流行率,潜在的机制和意义

Robyn Meech1, Dong Gui Hu1, Julie-Ann Hulin1

  • 1Discipline of Pharmacology, College of Medicine and Public Health, Flinders Health and Medical Research Institution (FHMRI), Flinders University, Bedford Park, Adelaide, Australia.

Expert opinion on drug metabolism & toxicology
|March 13, 2025
PubMed
概括

药物代谢中的性别差异,特别是涉及UDP-glucuronosyltransferases (UGTs),影响药物暴露和结果. 需要更多的研究来理解和解决药物治疗中的这些基于性别的变化.

关键词:
在UDP-glucuronosyl转移酶中.没有使用的GTs.药物代谢 药物代谢基因表达的基因表达方式葡萄糖化物 葡萄糖化物药物动力学 药物动力学性别差异的性别差异.性类固醇的使用.

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