了解心房动的老年癌症患者的死亡模式:全面的数据分析
Muhammad Abdullah Naveed1, Sivaram Neppala2, Shehroze Tabassum3
1Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
The American journal of the medical sciences
|March 13, 2025
概括
自1999年以来,65岁以上的癌症患者因心房 (AF) 的死亡率在美国翻了一番,在COVID-19大流行期间观察到显著增加. 有针对性的干预措施对于解决这一日益严重的公共卫生问题至关重要.
科学领域:
- 老年学是一门学科.
- 在瘤学瘤学.
- 心脏病学 心脏病学
背景情况:
- 在美国,心房动 (AF) 对患有癌症的老年人构成重大健康风险.
- 这项研究研究了65岁及以上癌症患者的死亡率趋势和AF人口差异.
研究的目的:
- 分析癌症患者 (65岁以上) 的AF年龄调整死亡率 (AAMR) 的趋势.
- 为了确定这一群体中AF相关死亡率的人口差异.
- 评估特定时间段,包括COVID-19大流行,对死亡率的影响.
主要方法:
- 利用CDC WONDER数据库提取从1999年到2023年的数据.
- 在癌症患者 (ICD-10 C00-C97) 中分析了AF (ICD-10 I48) 的年龄调整死亡率 (AAMR).
- 雇员joinpoint回归计算年平均百分比变化 (AAPC) 和年平均百分比变化 (APC),按性别,种族,地理和大都市地位分层.
主要成果:
- 从1999年到2023年,癌症患者的AF在美国65岁以上的成年人中造成了421,247例死亡.
- 整体AAMR从24.1增加到61.1 ,具有3.92%的显著整体AAPC.
- 死亡率在2018年至2021年间大幅上升 (APC:10.93%),男性,非西班牙裔白人和特定地理区域的死亡率更高.
结论:
- 美国癌症患者的AF的AAMR在过去二十年中翻了一番,在COVID-19大流行期间明显增加.
- 死亡率存在显著的人口差异,需要量身定制的公共卫生战略.
- 迫切需要有针对性的干预措施和改善医疗保健准入,以减轻这个脆弱人群中AF相关的死亡率.
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