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Updated: May 22, 2025

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一种YAP衍生的可以阻断YAP-TEAD信号传递,并抑制细胞增殖

Qiuyun Yuan1, Xiaoqiang Xia1, Yao Yuan1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China.

Cellular signalling
|March 13, 2025
PubMed
概括

研究人员开发了TBDi,这是一种针对YAP-TEAD相互作用的新型抑制剂. 这种有效地通过阻断YAP-TEAD转录活性来抑制癌细胞的增殖.

关键词:
细胞的增殖细胞的增殖.抑制剂的抑制剂在TBDi TBDi我们的 TEAD TEAD 团队.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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