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工业赞助的作用和近视控制干预的研究成果

Jia-Yan Kai¹, Hui-Min Chen¹, Xing-Xuan Dong¹

¹School of Public Health, Suzhou Medical College of Soochow University, Suzhou, China.

The British journal of ophthalmology

|March 13, 2025

概括

这项研究发现,在行业赞助和非行业赞助的近视控制随机对照试验 (RCT) 之间,结果或偏差风险没有显著差异. 然而,报告结论中的潜在行业偏见需要进一步调查.

科学领域:

眼科医生眼科眼科
临床试验临床试验
生物统计学生物统计学

背景情况:

控制近视的干预措施对于管理渐进的近视至关重要.
随机对照试验 (RCT) 是评估治疗疗效的黄金标准.
人们担心行业赞助的研究可能存在偏见.

研究的目的:

为了比较行业赞助与非行业赞助的近视控制RCT的结果和偏差风险.
评估赞助对研究结果和报告的影响.

主要方法:

在PubMed,Embase和MEDLINE的系统文献搜索到2023年10月.
包括报告球体等价值 (SE) 和/或轴长 (AL) 变化的RCT.
对聚合效应估计和偏差风险评估的元分析.

主要成果:

分析了93个RCT:43个由行业赞助和50个非行业赞助.
两组之间没有发现偏差风险或聚合效应估计的显著差异.
工业赞助与有利的研究结果没有显著的关联 (RR:0.98,OR:2.58).

结论:

工业赞助并没有显著影响近视控制RCT结果或偏差风险.
有限的负面结果可能会影响调查结果;报告结论存在行业偏见的可能性.
需要进一步的研究才能充分了解赞助对临床试验报告的影响.

关键词:

流行病学流行病学视觉视觉视觉视觉视觉是一个

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