从F-FDG PET测量总代谢瘤体积:一个现实检查
Ronald Boellaard1, Gerben J C Zwezerijnen2, Irène Buvat3
1Department of Radiology and Nuclear Medicine, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, The Netherlands; r.boellaard@amsterdamumc.nl.
概括
精确的总代谢瘤体积 (TMTV) 测量可以在不同的18F-FDG PET/CT软件平台上实现. 然而,处理时间的显著变化凸显了在临床实践中需要改进细分工作流程的需要.
科学领域:
- 核医学就是核医学.
- 瘤成像学成像学
- 医疗信息学 医疗信息学
背景情况:
- 使用18F-FDG PET/CT精确测量总代谢瘤体积 (TMTV),对于扩散性大B细胞淋巴瘤的管理至关重要.
- 当前的多层分段工作流程可能耗时且缺乏标准化.
研究的目的:
- 为了评估TMTV衍生在不同软件平台和阅读器上的准确性和效率.
- 确定临床TMTV细分工作流程需要改进的领域.
主要方法:
- 一项实地测试涉及5个基线18F-FDGPET/CT扫描从扩散大B细胞淋巴瘤患者.
- 10个不同的网站/阅读器使用各种商业软件平台和基准工作流程分析了扫描.
- 推导的TMTV值与参考值进行比较,并报告分析时间.
主要成果:
- TMTV的测量显示,在读者和平台之间,其准确性相当高,大多数值在基准值的10%以内.
- 观察到处理时间的显著变化,受读者体验和使用的软件的影响.
结论:
- 虽然TMTV可以准确地测量,但当前的细分工作流需要针对临床实践进行优化.
- 用户与软件供应商之间的加强协作对于提高TMTV细分效率和可靠性至关重要.
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