在患有不一致RFS和RSI得分的患者中的语音障碍
Feng Zhang1, Jinhong Zhang1, Dan Wang1
1Department of Otolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Journal of voice : official journal of the Voice Foundation
|March 13, 2025
概括
患有矛盾的喉回流 (LPR) 评分的患者面临更高的声音障碍的风险. 质子抑制剂 (PPI) 治疗有效地改善了语音质量,并减少了这个群体的症状.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 语音语言病理学 语音语言病理学
背景情况:
- 喉回流 (LPR) 是声障碍的已知危险因素之一.
- 逆流检测得分 (RFS) 和逆流症状指数 (RSI) 是LPR的诊断工具,其一致性往往很差.
- 不一致的RFS/RSI得分对语音障碍风险和PPI疗效的影响尚不清楚.
研究的目的:
- 评估RFS和RSI分数不一致的患者的语音障碍风险.
- 评估质子抑制剂 (PPI) 治疗在改善这个子组的语音症状和客观参数方面的有效性.
主要方法:
- 大样本后勤回归分析 (n=915) 随后进行病例对照研究 (n=200),并通过电话跟进.
- 对病例对照组进行了多变量逻辑回归分析.
- 一项前性干预研究评估了PPI治疗对语音症状和客观参数的影响.
主要成果:
- 与一致的负分数相比,不一致的RFS和RSI分数与患有语音障碍的风险更高显著相关.
- 质子抑制剂 (PPI) 治疗导致声音障碍指数 (VHI) 和GRBAS分数显著降低.
- 客观的语音参数在PPI治疗后显著改善.
结论:
- 不一致的RFS和RSI得分表明语音障碍的风险增加.
- PPI治疗有助于缓解症状并提高LPR分数不一致的患者的语音质量.
- 这一发现支持使用PPI来管理与LPR相关的语音障碍.
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