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Updated: May 22, 2025

Observation and Quantification of Telomere and Repetitive Sequences Using Fluorescence In Situ Hybridization FISH with PNA Probes in Caenorhabditis elegans
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通过免疫-Telo FISH检测端粒DNA损伤

Marianna Paulis1,2, Ombretta Garbarino1, Francesca Faggioli3,4

  • 1Institute of Genetics and Biomedical Research, UoS of Milan, National Research Council, Milan, Italy.

Methods in molecular biology (Clifton, N.J.)
|March 14, 2025
PubMed
概括

这项研究引入了一种结合免疫光在位杂交 (FISH) 方法,用于检测端粒的DNA损伤,这对于理解瘤基因诱导衰老 (OIS) 至关重要. 这种技术有助于识别功能障碍的端粒,并监测细胞培养和衰老细胞中的OIS.

关键词:
免疫-teloFISH 鱼类 鱼类在PML中,PML是PML.端粒是什么意思 端粒是什么意思γH2AXX 的时间.瘤基因诱导的衰老.

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