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在阿片类受体部分激动剂的结构导向设计

Balazs R Varga1, Sarah M Bernhard1, Amal El Daibani1

  • 1Center for Clinical Pharmacology, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.

Nature communications
|March 14, 2025
PubMed
概括

研究人员开发了C6-Quino,这是一种新的三角形阿片类受体 (δOR) 的部分激动剂. 这种非成性止痛药对缓解慢性疼痛,避免发作和其他阿片类药物副作用有很大的希望.

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