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Updated: May 22, 2025

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不同的鼻内用德克斯梅德托米丁剂量对儿科术后妄和兴奋的作用:网络元分析

Huan Wu1, Ping Wu1, Liubo Xiang1

  • 1Guizhou University of Traditional Chinese Medicine, Guiyang, China.

Pediatric research
|March 14, 2025
PubMed
概括

鼻腔内用德克斯梅德托米丁 (DEX) 有效地减少了麻醉后儿童出现的兴奋和妄想. 更高的DEX剂量,特别是2μg/kg,在预防动方面表现出最大的有效性.

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
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