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Updated: May 22, 2025

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
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对SNP从RNA-seq呼叫的基因型归算策略的比较分析

Kaixuan Guo1, Zhanming Zhong1, Haonan Zeng1

  • 1State Key Laboratory of Swine and Poultry Breeding Industry, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China.

BMC genomics
|March 14, 2025
PubMed
概括

使用RNA-SNP进行RNA测序 (RNA-seq) 基因型归算,比基于芯片的SNP提供更高的准确性. 这项研究为优化基因组和转录基因组研究中的RNA-SNP归算策略提供了指导.

关键词:
基因型的归算 基因型的归算猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪在RNA-seqqq.

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相关概念视频

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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