尿病中中性粒细胞与淋巴细胞的比率:系统性审查
Shokoufeh Khanzadeh1, Fatemeh Zarimeidani2, Erfan Kashani3
1Tabriz University of Medical Sciences, Tabriz, Iran.
BMC urology
|March 14, 2025
概括
中性粒细胞与淋巴细胞的比率 (NLR) 是尿病患者炎症的有效生物标志物. 升高的NLR水平表明急性或亚急性阶段,并可以预测并发症和石头通过.
科学领域:
- 医学研究 医学研究
- 生物标志物发现发现
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 尿病影响全球数百万人,需要负担得起的诊断生物标志物.
- 炎症在尿病进展中起着关键作用.
- 中性粒细胞与淋巴细胞比率 (NLR) 升高表明炎症和潜在的结石.
研究的目的:
- 审查和总结有关NLR在尿病中的作用的研究.
- 评估NLR作为尿病管理的潜在生物标志物.
主要方法:
- 在Scopus,PubMed和Web of Science数据库中进行系统的文献搜索,截至2023年1月1日.
- 在PROSPERO注册的研究 (CRD42024500756).
- 将33项相关研究纳入审查.
主要成果:
- 患有急性或亚急性尿病阶段的患者显示NLR水平明显高于健康对照组.
- 在急性和亚急性阶段之间,NLR水平有显著差异.
- 在尿病患者中,NLR预测了败血症,SIRS和自发性石头通行.
结论:
- 在临床环境中,NLR 作为一种可靠且易于实施的生物标志物.
- NLR有助于预测尿病患者的病情和结果.
- 支持NLR在尿病管理中的临床实用性.
相关概念视频
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