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Updated: May 6, 2026

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
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Published on: June 10, 2022

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基于模型的药物开发应用和机会在mRNA-LNP治疗中

Jiawei Zhou1, Rohit Rao2, Monica E Shapiro2

  • 1Pfizer Inc, Groton, Connecticut, USA.

Clinical pharmacology and therapeutics
|March 14, 2025
PubMed
概括

模型信息化药物开发 (MIDD) 通过整合安全性和有效性评估数据来帮助mRNA-LNP疗法. 这种方法通过利用各种建模技术和跨治疗模式的知识共享来增强临床开发.

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