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治疗急性骨髓性白血病的治疗方法与中枢神经系统的参与

Edwin U Suárez1, Tamara Castaño-Bonilla1, Rocio Salgado1

  • 1Hematology Hospital Universitario Fundación Jiménez Díaz.

Clinical hematology international
|March 14, 2025
PubMed
概括

中枢神经系统 (CNS) 参与急性髓性白血病 (AML) 提出了治疗挑战. 这次审查支持诊断腰部穿刺和向FLT3抑制剂,以改善中枢神经系统相关的AML的结果.

关键词:
FLT3 FLT3 在线播放急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.这是AML的外骨髓性表现.耐火性中枢神经系统白血病索拉芬尼布 (Sorafenib) 是一个

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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