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Updated: May 22, 2025

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein
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Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein

Published on: December 3, 2010

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输送器过量和集群使适应蛋白转移为细菌排放流的转移更加容易

Wenyao Zhang1,2,3,4, Christine E Harper5,6,7,4, Junsung Lee5,6

  • 1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.

Cell reports. Physical science
|March 14, 2025
PubMed
概括

研究人员在细菌多药物排泄中发现了一种穿机制,涉及过多的MacB转运器和动态的MacA适应蛋白. 这一发现为打击抗生素耐药性的新策略提供了机会.

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Transporters are essential membrane transport proteins with functions related to cell nutrition, homeostasis, communication, etc. Approximately 7% of all genes in the human genome code for transporters or transporter-related proteins.
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