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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.1K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.4K
The Thyroid Gland01:23

The Thyroid Gland

3.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.4K
Thermoregulation01:26

Thermoregulation

858
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
858
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.5K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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相关实验视频

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Thermal Ablation for the Treatment of Abdominal Tumors
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在甲状腺结节的热切除后,甲状腺功能发生变化.

Song Li1, Ming-An Yu1, Zhen-Long Zhao1

  • 1China-Japan Friendship Hospital, Beijing, China.

Frontiers in endocrinology
|March 14, 2025
PubMed
概括

热切除掉 (TA) 对甲状腺功能的影响很小,FT3,FT4和TSH水平的持续变化很小. 取消前的TSH,哈西莫托

科学领域:

  • 内分泌学 在内分泌学.
  • 在瘤学瘤学.
  • 医疗成像医学成像

背景情况:

  • 甲状腺结节很常见,热性除 (TA) 是一种新兴的治疗选择.
  • 了解TA对甲状腺功能的影响对于患者管理至关重要.
  • 鉴定甲状腺功能障碍后的风险因素可以优化治疗策略.

研究的目的:

  • 为了评估甲状腺功能在甲状腺结节的TA后的变化.
  • 为了确定切除后甲状腺功能障碍的预测因素.

主要方法:

  • 对2264名接受TA治疗的患者进行了对良性甲状腺结节或乳头甲状腺癌的回顾性分析.
  • 测量TSH,FT3和FT4水平在去除前以及在去除后多个时间点,最多12个月.
  • 统计分析以确定甲状腺功能异常的危险因素.

主要成果:

  • 在TA后12个月内观察到FT3,FT4和TSH水平的轻微持续变化.
  • 甲状腺功能异常的总发病率为5.07%,其中1名患者需要治疗.
  • 乳头甲状腺癌病例显示,与良性结节相比,异常发生率更高.
  • 切除前的TSH,哈希莫托甲状腺炎和多重结节是切除后甲状腺功能障碍的重要危险因素.
关键词:
良性甲状腺结核是什么皮囊甲状腺癌是甲状腺癌.热性剥离的热性剥离甲状腺功能 甲状腺功能甲状腺结节 甲状腺结节

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Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
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结论:

  • TA对整体甲状腺功能的影响最小.
  • 提升的前移除TSH,哈西莫托甲状腺炎的存在和多个结节是后TA甲状腺功能障碍的关键风险因素.
  • 基于这些因素的风险分层可以帮助个性化患者护理.