相关实验视频
Updated: May 22, 2025

10:02
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
31.7K
在眼内抗血管性疗法中对药物监督
1Department of Ophthalmology, Yerevan State Medical University, Yerevan, Armenia.
Cutaneous and ocular toxicology
|March 14, 2025
概括
用于视网膜疾病的抗VEGF药物可能会导致系统性副作用,如心血管和神经问题. 意识和及时管理对于患者安全至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
- 心血管研究研究心血管研究
背景情况:
- 抗VEGF药物对于治疗视网膜疾病至关重要,导致内内注射增加.
- 对这些广泛使用的抗VEGF药物的系统安全性产生了担忧.
研究的目的:
- 批判性地分析目前关于眼科实践中使用的抗VEGF药物的系统安全性的研究结果.
主要方法:
- 在PubMed,科学网络和谷歌学者 (2012年1月至2025年2月) 进行了全面的文献搜索.
- 在审查参考清单和应用排除标准后,选出了84篇相关文章.
主要成果:
- 临床证据表明,眼内抗VEGF治疗可以导致全身不良事件.
- 潜在的系统性副作用包括心血管,脏和神经方面的并发症.
结论:
- 医疗专业人员必须意识到与抗VEGF治疗相关的全身风险,特别是在糖尿病患者或老年患者中.
- 早期识别和管理系统性副作用对于改善患者的治疗结果至关重要.
更多相关视频
06:19Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
Published on: May 31, 2024
666
05:14Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
991
相关概念视频
Pharmacovigilance
763
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
763
Open Angle Glaucoma: Treatment
378
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
378
Angle Closure Glaucoma: Treatment
420
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
420
Glaucoma: Overview
488
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
488