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Updated: May 22, 2025

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在部分解盲样本大小重新估计时保存I型错误

Ann Marie K Weideman1,2, Kevin J Anstrom1,2, Gary G Koch1

  • 1Department of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Statistics in medicine
|March 14, 2025
PubMed
概括

本研究引入了一种在临床试验中进行样本大小重新估计 (SSR) 的新型部分不盲目的方法. 这种方法保持了I型错误率,同时允许基于二进制和连续结果的中间数据进行调整.

关键词:
适应性设计是适应性的设计.进行中期分析分析.调整样本大小的调整.保存I型错误的保护方法不平等待遇分配不平等的待遇分配变量异质性的异质性

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