通过巴顿 - 凯洛格精化转化基基基基的转化
Anthony Linden1, Daniel H Egli1, Heinz Heimgartner1
1Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Acta crystallographica. Section C, Structural chemistry
|March 14, 2025
概括
巴顿 - 凯洛格油脂化转化使用二化合物将二氧化碳化物转化为基. 晶体结构揭示了烯和烯构造,弱相互作用影响了它们的形状和超分子组合.
科学领域:
- 有机化学 有机化学
- 晶体学 晶体学是指结晶学.
- 超分子化学 超分子化学
背景情况:
- 巴顿 - 凯洛格油脂化是一种合成方法,用于将硫基化合物转化为基.
- 这种反应涉及用一种二化合物和三酸逐步处理.
- 了解中间体和产品的结构和结构性质对于阐明反应机制至关重要.
研究的目的:
- 用模型化合物研究巴顿 - 凯洛格烯化:4,4'-dimethoxythiobenzophenone和diazocyclohexane.
- 为了确定中间体硫和最终的烯产品的晶体结构.
- 分析这些化合物的结构偏好和分子间相互作用.
主要方法:
- 巴顿 - 凯洛格油化反应.
- 单晶X射线衍射用于结构确定.
- 对分子几何学,形状和超分子组件的分析.
主要成果:
- 合成和结晶结构的确定[bis(4-methoxyphenyl) methylidene]环素和中间产物2,2-bis(4-methoxyphenyl)-1-thiaspiro[2.5]octane的合成和结晶结构的确定.
- 形状和几何形状与相关的文献结构一致;除了 tert-butyl 组外,对 thiirane 环的替代效应是最小的.
- 微弱的分子内C-H...S相互作用影响了二烯构造,而C-H...π相互作用驱动了二烯的3D超分子结构.
结论:
- 该研究提供了关于巴顿-凯洛格油脂精炼产品和中间产品的详细结构见解.
- 弱相互作用在决定分子构造和超分子组织方面发挥着重要作用.
- 该方法被扩展到合成1,2-二二醇衍生物,进一步证明了反应的多功能性.
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