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Updated: May 22, 2025

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血红素-1 结合于整合素β3,通过抑制NF-κB通路来抑制血管化

Fang Liu1, Qingchun Liang2, Li Li3

  • 1Department of Cardiology, Laboratory of Heart Center, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation; Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Guangzhou, PR China.

The Journal of pathology
|March 14, 2025
PubMed
概括

血栓素1 (THBS1) 通过与整合素β3相互作用并抑制NF-κB通路,抑制慢性病 (CKD) 中的血管化. 这一发现表明THBS1是CKD患者血管化的潜在治疗标.

关键词:
在 NF-κBB 中.慢性脏疾病 慢性脏疾病细胞外矩阵是细胞外矩阵.整体蛋白 β3 的组成.血小板蛋白 1 1血管化 血管化

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