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Updated: May 22, 2025

Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion
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Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion

Published on: April 4, 2025

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老化和BRCA突变的干细胞驱动上皮细胞转化

Geyon L Garcia1, Taylor Orellana2, Grace Gorecki1

  • 1University of Pittsburgh Medical Center, Pittsburgh, PA, United States.

Cancer discovery
|March 14, 2025
PubMed
概括

高风险的介质细胞/干细胞 (hrMSCs) 通过改变输卵管细胞来驱动高等级的血清性卵巢癌的发病. 这些hrMSC与BRCA1/2突变和衰老有关,为早期检测和预防提供了新的途径.

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