未满足的社会需求和体炎:一个表型化算法和横截面分析
Thomas E Ueland1, Samuel A Younan2, Parker T Evans3,4
1Vanderbilt University School of Medicine, Nashville, TN 37232, United States.
概括
一个经过验证的算法可以准确地识别分歧性疾病的严重程度. 未满足的社会需求,如粮食不安全,与更严重的分泌体炎病例有关,这表明需要有针对性的临床干预.
科学领域:
- 医疗信息学医学信息学
- 公共卫生 公共卫生
- 胃肠病学 胃肠病学
背景情况:
- 发 diverticular 疾病的严重程度有很大的差异.
- 健康的社会决定因素会影响疾病的表现和结果.
- 准确的表型定型对于了解疾病负担至关重要.
研究的目的:
- 验证一种表型算法,用于分类分歧性疾病的严重程度.
- 调查未满足的社会需求与关节疾病严重程度之间的关联.
主要方法:
- 开发并验证了一种表型算法,用于分泌腺炎,轻度分泌腺炎和严重/复发性分泌腺炎.
- 将算法应用于来自我们所有人的研究计划的队列.
- 分析了社会障碍 (粮食不安全,住房不稳定,护理准入) 在贫困水平的分布.
- 使用后勤回归来评估社会需求与疾病严重程度之间的关联.
主要成果:
- 该表型算法表现出高准确性,具有从0.87到0.97的正预测值和从0.97到0.99.9的负预测值.
- 未得到满足的社会需求在贫困五分位数中呈现出可变的分布.
- 在未满足的社会需求和手术性或复发性住院分泌体炎 (OR 1.61 [95% CI 1.19-2.17]) 与分泌体炎相比增加的几率之间发现了联系.
结论:
- 一个经过验证的表型算法有效地分类分歧性疾病的严重程度.
- 未满足的社会需求与更严重的分泌体炎症状有显著的关联.
- 了解疾病特定群体内的社会障碍,可以指导针对性的临床干预.
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