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PFAS诱导的土壤微生物中的脂肪酸代谢障碍:依赖于碳链长度,头组和附着的以太

Enhui Wu¹, Kun Wang^1,2, Jingqing Zhou³

¹Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.

Environmental science & technology

|March 14, 2025

概括

和多醇基物质 (PFAS) 根据其结构不同地影响土壤微生物. 微生物脂肪酸概况可以作为PFAS毒性和土壤健康的生物标志物.

科学领域:

环境化学环境化学
微生物生态学微生物生态学
毒理学毒理学毒理学

背景情况:

和多基基物质 (PFAS) 是持久的环境污染物.
它们对土壤微生物和有毒机制的影响尚未完全理解.
在链条长度,头组和替代形式上,PFAS结构存在很大差异.

研究的目的:

研究PFAS对微生物脂肪酸 (FA) 概况的结构依赖性影响.
确定潜在的代谢生物标志物,以评估PFAS在土壤中的毒性.
为了阐明PFAS对土壤微生物的有毒机制.

主要方法:

综合实地和实验室调查.
基于PFAS和FA结构的PFAS-FA相互作用模式的分析.
使用*Pseudomonas aeruginosa*PAO1进行实验室验证,以研究代谢干扰.

主要成果:

观察到明显的PFAS-FA相互作用模式,根据PFAS链长度,功能组和FA特征而有所不同.
长链PFCA和PFSA不同影响中长链和单不和FA.
替代PFAS结构如PFECA和短链变体与多不和脂肪酸有关.
实验室研究证实了FA的代谢干扰,并揭示了对脂,乙-CoA,二次代谢物,膜合成,C/N代谢和质量检测的更广泛影响.

结论:

PFAS对微生物的FA形状和新陈代谢产生结构依赖的作用.
微生物FA概况可以作为PFAS毒性的敏感生物标志物.
了解这些影响对于评估污染环境中的土壤健康至关重要.

关键词:

在PFAS中,我们可以使用PFAS.其他 PFAS 替代品脂肪酸的新陈代谢.微生物的代谢物.土壤细菌是土壤中的细菌.

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