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Updated: May 22, 2025

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QRICH1通过CARD11信号体通过CD8+T细胞激活的细胞内检查点进行介导

Nicole M Carter1, Wihib D Hankore1, Yong-Kang Yang1

  • 1Department of Biological Chemistry and Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Science immunology
|March 14, 2025
PubMed
概括

富含谷氨胺的蛋白1 (QRICH1) 通过调节卡斯帕斯招募域含蛋白11 (CARD11) 信号传递,作为 CD8+ T 细胞激活的检查点. 这一发现提升了对免疫反应微调的理解.

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