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Updated: May 22, 2025

Site Specific Lysine Acetylation of Histones for Nucleosome Reconstitution using Genetic Code Expansion in Escherichia coli
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对cGAS-STING路径的规定

Bing Zhang1, Pengbiao Xu1, Andrea Ablasser1,2

  • 1Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland;

Annual review of immunology
|March 14, 2025
PubMed
概括

循环GMP-AMP合成酶 (cGAS) -cGAMP-STING通路防御病原体,但需要调节以防止自我DNA激活. 了解它的检查点是操纵健康和疾病中DNA触发免疫力的关键.

关键词:
检测DNA的感应器刺痛是一种刺痛.cGAS 是一个气体.循环二核酸是循环的二核酸.免疫系统的恒常性.这是先天的免疫力.

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