住院儿童感染相关死亡率:2016年至2021年在中国的多中心研究
Jiao Tian1, Qi Li2, Shiqi Cai3
1Laboratory of Infection and Virology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China; Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children, Beijing, China; Research Unit of Critical Infection in Children, 2019RU016, Chinese Academy of Medical Sciences, Beijing, China; Department of Respiratory, Tianjin Children's Hospital, Tianjin, China.
感染导致了中国住院儿童的显著死亡率. 在COVID-19大流行期间,与大流行前相比,感染相关的死亡人数较少,败血症是主要原因.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 住院儿童面临来自感染的死亡风险.
- 中国严格的COVID-19措施影响了病原体传播和感染流行病学.
- 富邦研究中心自2016年以来一直在收集儿科出院医疗记录数据.
研究的目的:
- 调查中国住院儿童感染相关死亡率.
- 分析COVID-19大流行之前和期间感染的儿科死亡趋势.
- 确定儿科感染中常见的死亡原因和病原体.
主要方法:
- 分析了来自中国27家高等儿童医院 (2016-2021) 的出院医疗记录 (FSMR) 的表单.
- 包括因感染而死亡的18岁或以下的住院儿童.
- 收集的数据包括人口统计,地区,入院年,死亡原因,病原体和逗留时间.
主要成果:
- 1130名儿童死于感染,占所有死亡人数的18.8%.
- 在不同的人口统计数据中,男孩的死亡率高于女孩.
- 在COVID-19期间 (2020-2021) 与COVID-19前时代相比,感染相关死亡人数有所下降.
- 败血症是最常见的死亡原因,其次是肺炎和中枢神经系统感染.
- 在30.6%的病例中确定了病原体,包括细菌,病毒和真菌.
结论:
- 感染仍然是中国住院儿童死亡的重要原因.
- 这项研究强调了COVID-19大流行对儿科感染相关死亡的影响.
- 败血症和肺炎是儿童重症监护干预的关键领域.
相关概念视频
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Viral Mutations
Lung Capacity
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...


